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Geistlich Bio-Gide®

Geistlich Bio-Gide® is the leading collagen membrane for oral tissue regeneration1,2. It is used in combination with a bone substitute such as Geistlich Bio-Oss® or Geistlich Bio-Oss® Collagen. Due to its bilayer structure, the membrane not only prevents ingrowth of soft tissue into the augmented site, but also acts as a guide for the appropriate cascade of bone, soft tissue and blood vessel development.

Geistlich Bio-Gide® is naturally resorbable and does not have to be removed in a second surgery. As it simplifies the operation technique, and thanks to its remarkable wound healing properties3,4, Geistlich Bio-Gide® has fundamentally changed dental bone regeneration.

“The Geistlich Bio-Gide® membrane has, for more than 15 years, proven itself to be reliable and is characterized by a very low complication rate.”
Prof. Daniel Buser, Berne, Switzerland


Leading clinicians rely on Geistlich Bio-Gide® for:

  • Very good tissue integration5,6 and strongly enhanced bone regeneration compared to using only a bone substitute7,8.
  • Native collagen structure leads to fewer dehiscence compared with other available membranes3,4,9.
  • Simplified surgery without removal of the membrane.
  • Pleasing outcomes in the aesthetic zone10.
  • Long-term data over 12 to 14 years shows predictable results of GBR treatments with Geistlich Bio-Oss® and Geistlich Bio-Gide®11.

In the 1990s, Dr. Peter Geistlich was the first to develop a natural collagen membrane that optimally meets the requirements for regenerative dentistry. Meanwhile Geistlich Bio-Gide® is the leading collagen membrane1,2, validated by 18 years of successful use in more than two million patients and documented in more than 200 scientific publications12.


  1. iData Research Inc., US Dental Bone Graft Substitutes and other Biomaterials Market, 2011.
  2. iData Inc., European Dental Bone Graft Substitutes and other Biomaterials Market, 2012.
  3. Tal H, et al.: Clin. Oral Implants Res 2008; 19: 295-302.
  4. Zitzmann NU, et al.: Int J Oral Maxillofac Implants 1997; 12: 844-52.
  5. Schwarz F, et al.: Clin Oral Implants Res 2006; 17: 403-09.
  6. Schwarz F, et al.: Clin Oral Implants Res 2008; 19(4): 402-15.
  7. Perelman-Karmon et al.: Int J Periodontics Restorative Dent 2013, 32(4): 459-65.
  8. Wallace SS, et al.: Int J Periodontics Restorative Dent 2005; 25(6): 551-59.
  9. Becker J, et al.: Clin. Oral Implants Res 2009; 20(7): 742-93.
  10. Buser D, et al.: J Periodontol 2011; 82(3): 342-49.
  11. Jung RE, et al.: Clin Oral Implants Res. 2013; 24(10):1065-73.
  12. Pubmed September 2013. Search Term: Bio-Gide.
Verena Vermeulen
Group Lead Clinical Marketing