
Geistlich Bio-Gide®
Geistlich Bio-Gide® is the leading collagen membrane for oral tissue regeneration1,2. It is used in combination with a bone substitute such as Geistlich Bio-Oss® or Geistlich Bio-Oss® Collagen. Due to its bilayer structure, the membrane not only prevents ingrowth of soft tissue into the augmented site, but also acts as a guide for the appropriate cascade of bone, soft tissue and blood vessel development.
Unique bilayer structure of Geistlich Bio-Gide® (SEM, stained blue, 100x).
High similarity of Geistlich Bio-Gide® to human collagen (SEM 2000x, Prof. Dr. Brenner).
Geistlich Bio-Gide® is naturally resorbable and does not have to be removed in a second surgery. As it simplifies the operation technique, and thanks to its remarkable wound healing properties3,4, Geistlich Bio-Gide® has fundamentally changed dental bone regeneration.
Leading clinicians rely on Geistlich Bio-Gide® for:
- Very good tissue integration5,6 and strongly enhanced bone regeneration compared to using only a bone substitute7,8.
- Native collagen structure leads to fewer dehiscence compared with other available membranes3,4,9.
- Simplified surgery without removal of the membrane.
- Pleasing outcomes in the aesthetic zone10.
- Long-term data over 12 to 14 years shows predictable results of GBR treatments with Geistlich Bio-Oss® and Geistlich Bio-Gide®11.
In the 1990s, Dr. Peter Geistlich was the first to develop a natural collagen membrane that optimally meets the requirements for regenerative dentistry. Meanwhile Geistlich Bio-Gide® is the leading collagen membrane1,2, validated by 18 years of successful use in more than two million patients and documented in more than 200 scientific publications12.
References:
- iData Research Inc., US Dental Bone Graft Substitutes and other Biomaterials Market, 2011.
- iData Inc., European Dental Bone Graft Substitutes and other Biomaterials Market, 2012.
- Tal H, et al.: Clin. Oral Implants Res 2008; 19: 295-302.
- Zitzmann NU, et al.: Int J Oral Maxillofac Implants 1997; 12: 844-52.
- Schwarz F, et al.: Clin Oral Implants Res 2006; 17: 403-09.
- Schwarz F, et al.: Clin Oral Implants Res 2008; 19(4): 402-15.
- Perelman-Karmon et al.: Int J Periodontics Restorative Dent 2013, 32(4): 459-65.
- Wallace SS, et al.: Int J Periodontics Restorative Dent 2005; 25(6): 551-59.
- Becker J, et al.: Clin. Oral Implants Res 2009; 20(7): 742-93.
- Buser D, et al.: J Periodontol 2011; 82(3): 342-49.
- Jung RE, et al.: Clin Oral Implants Res. 2013; 24(10):1065-73.
- Pubmed September 2013. Search Term: Bio-Gide.

- Geistlich Bio-Oss® and Geistlich Bio-Gide® - Product Information
- Treatment concept for extraction sockets
- Treatment concept for periodontal surgery
- Patient information - General
- Patient information - Extraction socket
- Patient information video – Minor bone augmentation
- Patient information video – Extraction socket management
- Patient information video – Sinus floor elevation