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Perio-System Combi-Pack

Perio-System Combi-Pack combines the improved handling attributes of Geistlich Bio-Oss® Collagen 100 mg and Geistlich Bio-Gide® Perio 16 x 22 mm. Used together, they offer optimal properties for regenerative periodontal procedures.

User benefits

  • Proven effectiveness in regenerative periodontal therapy1-6.
  • Sustained higher attachment level gain compared with open flap debridement alone7.
  • Easier handling and forming of Geistlich Bio-Oss® Collagen and Geistlich Bio-Gide® Perio simplify periodontal treatment.
  • Long-term volume stability, bone integration and space maintenance8-14.

Perio-System Combi-Pack is available in a convenient combination package:

  • Geistlich Bio-Gide® Perio 16 x 22 mm with sterile templates
  • Geistlich Bio-Oss® Collagen 100 mg
“Regenerative periodontal surgery in combination with Geistlich Bio- Oss® Collagen and Geistlich Bio-Gide® Perio results in markedly improved clinical and radiographic outcome.”
Dr. Beat Wallkamm, Langenthal, Switzerland


Geistlich Bio-Oss® Collagen is a natural bone substitute that maintains long-term volume and enhances new bone formation. The Geistlich Bio-Oss® Collagen block is formable and easy to position into the defect site.

Geistlich Bio-Gide® Perio is a collagen membrane with improved handling characteristics for periodontal applications. The smooth upper surface slows absorption of moisture and allows more time for exact positioning. The firmer material facilitates cutting when dry, making it optimal for guided tissue regeneration.



  1. Cosyn J, et al.: J Clin Periodontol 2012; 39(10): 979-86.
  2. Camelo Int J Periodontics Restorative Dent 1998; 18(4): 321-31.
  3. Camargo PM, et al.: J Clin Periodontol 2000; 27(12): 889-96.
  4. Sculean A, et al.: J Clin Periodontol 2003; 30(1): 73-80.
  5. Tonetti MS, et al.: J Clin Periodontol 2004; 31(9): 770-76.
  6. Linares M, et al.: J Clin Periodontol 2006 May; 33(5): 351-58.
  7. Sculean A, et al.: J Clin Periodontol 2007 Jan; 34(1): 72-77.
  8. Orsini G, et al.: J Biomed Mater Res B: Appl Biomater 74B, 2005; 448-57.
  9. Jung RE, et al.:  Clin Oral Implants Res 2013; 24(10): 1065-73.
  10. Aghaloo TL, Moy PK: Int J Oral Maxillofac Implants 2007; 22: 49-70.
  11. Jung RE, et al.: J Clin Periodontol 2013; 40(1): 90-98.
  12. Traini T, et al.: J Periodontol 2007; 78: 955–61.
  13. Mordenfeld A, et al.: Clin Implant Dent Relat Res 2012, Oct 15 (Epub ahead of print).
  14. Galindo-Moreno P, et al.: Clin Implant Dent Relat Res 2012, Feb 29 (Epub ahead of print).


Verena Vermeulen
Group Lead Clinical Marketing