We use cookies to give you the best experience possible with our website and to improve our communication with you. We consider your selection and will only use the data you have approved us to gather.

These cookies help making a website usable by enabling basic functions like page navigation and access to secure areas of the website. The website cannot function properly without these cookies.

These cookies help website owners to understand how visitors interact with websites by collecting and reporting information anonymously. With this information we can constantly improve the experience we offer on our website.

These cookies are used to track visitors across websites. The intention is to display ads that are relevant and engaging for the individual user and thereby more valuable for publishers and third party advertisers.

Gain of keratinised tissue

The band of keratinized tissue around teeth and implants is considered to be important in maintaining functionality and esthetics. It also enables patients to maintain good oral hygiene without irritation or discomfort.1,2

The width of the keratinized mucosa around an implant might also influence the risk of peri-implantitis.3 This remains a controversial issue.4

Autogenous soft tissue grafts, such as free gingival graft or connective tissue grafts, have proven successful in creating additional keratinized tissue around teeth and implants.5 However, harvesting those grafts, usually from the palate, is painful, technically demanding, time consuming and may lead to complications such as bleeding, pain, swelling, and occasionally also numbness or infections.6-9

Several studies have shown successful outcomes with Geistlich Mucograft®. The collagen matrix creates the same amount of keratinized tissue as connective tissue grafts10 or free gingival grafts5,11 and helps to regenerate a keratinized tissue that resembles the surrounding native gingiva.12 Compared to autologous grafts the matrix produces a better color and texture match with the surrounding tissue that remains stable in the long term.13



  1. Schrott AR, et al.: Clin Oral Implants Res 2009; 20(10): 1170-77. (clinical study)
  2. Chung DMT, et al.: J Periodontol 2006; 77(8): 1410-20. (clinical study)
  3. Schwarz F, et al.: J Periodontol 2018; 89 Suppl 1: S267-S290. (review)
  4. Greenstein G, Cavallaro J: Compend Contin Educ Dent 2011; 32(8): 24-31. (review)
  5. Thoma DS, et al.: Clin Oral Investig 2018; 22(5): 2111-19. (clinical study)
  6. Griffin TJ, et al.: J Periodontol 2006; 77: 2070-79. (clinical study)
  7. Soileau KM, et al.: J Periodontol 2006; 77: 1267-73. (clinical study)
  8. Zucchelli G, et al.: J Clin Periodontol 2010; 37: 728-38. (clinical study)
  9. Cairo F, et al.: J Clin Periodontol 2012; 39: 760-68. (clinical study)
  10. Lorenzo R, et al.: Clin Oral Implants Res. 2012; 23(3): 316-24. (clinical study)
  11. Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73. (clinical study)
  12. Schmitt CM, et al.: J Periodontol 2013; 84: 914-23. (clinical study)
  13. Schmitt CM, et al.: Clin Oral Implants Res 2016; 27(11): e125-e133. (clinical study)
Verena Vermeulen
Group Lead Clinical Marketing