Soft-tissue regeneration

Soft-tissue regeneration has become increasingly important in restoring functionality and esthetic appearance.

The standard materials for soft-tissue regeneration are autogenous free gingival grafts and connective tissue grafts, but harvesting soft-tissues from the palate is painful, technically demanding and time consuming.

Off-the-shelf soft-tissue products, such as Geistlich Fibro-Gide®, Geistlich Mucograft® and Geistlich Mucograft® Seal, offer many advantages over autogenous grafts harvested from the palate.

  • No donor site means less pain,1,2 morbidity3 and surgical chair-time.1,2,4
  • Natural texture and color match to surrounding native tissue when increasing keratinized tissue.5,6


Use of Geistlich Fibro-Gide® is approved for treatment of

  • Insufficient soft-tissue volume around natural teeth and implants
  • Recession defects

Use of Geistlich Mucograft® is approved for treatment of

  • Recession defects 
  • Widening of the keratinized tissue around teeth or implants

Use of Geistlich Mucograft® Seal is approved for treatment of

  • the therapeutic areas
  • Socket sealing in extraction socket management



  1. Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76.
  2. Geistlich Mucograft® Seal Advisory Board Meeting Report, 2013. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland.
  3. Griffin TJ, et al.: J Periodontol 2006; 77(12): 2070-79.
  4. Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24.
  5. McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17.
  6. Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73. 
    Verena Vermeulen
    Senior Scientific Communication Manager