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Soft-Tissue Thickness Augmentation

Why is it worthwhile to thicken the soft tissue around dental implants or natural teeth or under bridge restorations? The red-white esthetics and the expectations of the patient often play a role.1-4 However, studies also show that patients with a thin mucosal biotype are more susceptible to functional and esthetic problems.5

To date, subepithelial connective tissue is considered the gold standard for the augmentation of soft tissue.6,7 Yet, anatomical factors such as nerves and blood vessels in the palate restrict the dimensions of the grafts8-10. In addition, graft harvesting may cause bleeding, pain, swelling, and occasionally also numbness or infections.11-14

Soft tissue thickening with Geistlich Fibro-Gide® has been investigated in several pre-clinical and clinical trials. The studies showed comparable results to connective tissue grafts in terms of change in soft tissue volume over time.7 Geistlich Fibro-Gide® has been proven to provide a stable augmented soft tissue both in terms of quality and quantity with the additional benefits of eliminating the donor site, shorter surgical time and lower patient pain perception.15-17



  1. Studer SP. et al.: J Prosthet Dent 2000; 83(4):402-11. (clinical study)
  2. Kinsel RP, Capoferri D, et al. : Pract Proced Aesthet Dent 2008; 20(4): 231-36. (clinical report)
  3. Schneider D, et al.: Clin Oral Implants Res 2011; 22(1): 28-37. (clinical study)
  4. De Bruyckere T, et al. : J Clin Periodontol 2015; 42(9): 876-82. (clinical study)
  5. Puisys A, Linkevicius T: Clin Oral Implants Res 2015; 26(2): 123-29. (clinical study)
  6. Thoma DS, et al.: Clin Oral Implants Res 2009; 20: 146-65. (systematic review)
  7. Thoma DS, et al.: J Clin Periodontol 2014; 41 Suppl 15: S77-91. (systematic review)
  8. Fu JH, et al.: J Periodontol 2011; 82: 1000-06. (cadaver study)
  9. Kim DH, et al.: Clin Anat 2014; 27: 578-84. (cadaver study)
  10. Yu SK, et al.: J Clin Periodontol 2014 ; 41(27): 908-13. (cadaver study)
  11. Griffin TJ, et al.: J Periodontol 2006; 77: 2070-79. (clinical study)
  12. Soileau KM, et al.: J Periodontol 2006; 77: 1267-73. (clinical study)
  13. Zucchelli G, et al.: J Clin Periodontol 2010; 37: 728-38. (clinical study)
  14. Cairo F, et al.: J Clin Periodontol 2012; 39: 760-68. (clinical study)
  15. Zeltner M, et al. J Clin Periodontol 2017; 44(4): 446-53. (clinical study)
  16. Thoma DS, et al. J Clin Periodontol 2016; 43(10): 874-85. (clinical study)
  17. Huber S, et al.: J Clin Periodontol 2018; 45(4): 504-12. (clinical study)
Verena Vermeulen
Group Lead Clinical Marketing